Assessment & material selection
The doctor performs an anatomical evaluation and assesses skin quality, selecting the appropriate biostimulator for the desired result.
Non-Surgical
Collagen Biostimulators
Natural collagen activation for deep tightening and radiance.
ResultNatural-looking
Pain levelMild discomfort
Session duration10–20 minutes
RecoveryImmediate return
What it is – What it offers
Biostimulators: naturally awakening collagen from within.
Biostimulators are one of the most important developments in modern aesthetic medicine. These injectable substances — unlike classic fillers (hyaluronic acid) — do not provide immediate or artificial volume. Instead, they act as a powerful "awakening mechanism" for the body itself.
Biostimulators activate fibroblasts to produce new, natural collagen and elastin. Their action delivers a gradual, progressive and long-lasting improvement in skin quality, restoring lost firmness, density and natural radiance.
- Natural collagen activation — no foreign material introduced into the body.
- Gradual, visible improvement in tightening and radiance within 2–4 weeks.
- Long-lasting results: 12–24 months depending on the biostimulator type.
- Suitable both preventively (from age 25–30) and correctively.
Biostimulators
Treatment areas
Where are biostimulators applied?
Biostimulator treatment has a wide range of applications — both preventively and therapeutically on the face and body.
- FaceOverall rejuvenation and laxity treatment — improved texture, firmness and radiance.
- Around the eyes & neckAreas with delicate skin that benefit particularly from natural collagen renewal.
- Décolletage & dorsal handsRestoration of lost elasticity and radiance in areas that "reveal" age.
- Body (abdomen, arms, thighs, buttocks)Tightening and texture improvement at areas showing laxity or following weight loss.
Beauty by Design
The body produces. The result develops gradually.
Collagen biostimulators work beneath the skin to gradually rebuild firmness and elasticity, for a natural, progressive result.
How the treatment is performed
Biostimulator application step by step.
Treatment is performed in the clinic following a personalised protocol.
Preparation & marking
The area is thoroughly cleansed. If necessary, topical anaesthetic cream is applied for comfort, and target points are marked.
Material injection
The biostimulator is injected with precision at the correct skin depth using a very fine needle or specialised microcannula.
Instructions & follow-up
Clear aftercare instructions are provided for the following days to support the collagenesis process.
Preparation before treatment
How to prepare for biostimulators.
To minimise the risk of bruising and support a comfortable experience:
- Avoid medications that affect blood clotting (aspirin, ibuprofen, NSAIDs) for 5–7 days before — always in consultation with your own doctor.
- If you arrive wearing make-up, careful cleansing is performed before treatment.
Quick Facts
Collagen biostimulators at a glance.
- Treatment duration
- 10–20 minutes, depending on the area treated.
- Anaesthesia
- None required, or topical anaesthetic cream applied.
- Pain level
- Minimal sting or sensation of light pressure, without intense pain.
- Season
- Throughout the year.
- Return to activities
- Immediate.
- First results
- Within 2–4 weeks (radiance, texture); final result at 3–6 months.
- Duration of results
- 12–24 months depending on the biostimulator type.
Recovery
What to expect after treatment.
First hours
Immediate return to daily routine. Mild redness, slight swelling or sensitivity at injection sites may occur — these resolve quickly.
Bruising
Minor bruising is expected and resolves within a few days — it can be easily covered with make-up from the following day.
What to avoid (first 24–48 hours)
Avoid intense physical exercise, sauna, steam bath and direct sun exposure.
Rare cases
Rarely, small nodules may form under the skin — palpable but easily managed by the doctor. Very rarely, an infection or allergic reaction may occur.
Personalised
Approach
Approach
FAQ
Frequently asked questions about biostimulators.
Classic fillers provide immediate, mechanical volume to fill wrinkles or add shape (e.g. to lips or cheekbones). Biostimulators do not add volume — they stimulate the body itself to produce new collagen, gradually and naturally improving the density, firmness and elasticity of the entire skin area.
The protocol is individualised, but 2–4 sessions are typically required with a few weeks between them, depending on the skin's needs and the material selected.
Due to natural collagen production, results can last, typically 12 to 24 months, depending on the type of biostimulator and individual skin characteristics.
There is no strict age limit. Treatment is usually started preventively or correctively from the late twenties or early thirties — the period when natural, gradual collagen reduction begins in the body.
Start with a personal consultation.
Assess your skin condition and design a personalised collagen biostimulation protocol.
Results vary from person to person and cannot be guaranteed. Suitability for any treatment is determined by the doctor after a personal consultation.